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Apr 1, 2020 · An option for these patients is domperidone , a peripherally acting dopamine antagonist that does not cross the blood–brain barrier 1 Dopamine antagonists should be avoided in children due to the high incidence of extrapyramidal symptoms, particularly dystonic reactions People also askIs domperidone a refractory drug? Domperidone : Unapproved Alternative to Metoclopramide We noted the recent information in the Journal about metoclopramide use and its risk of neurologic adverse effects such as tardive dyskinesia 1 , 2 Shaffer et al 1 Aug 7, 2018 · Key Points Metoclopramide is generally considered a safe alternative for domperidone Our patient developed severe cardiac adverse effects after intravenous metoclopramide Be aware of cardiac adverse effects in elderly treated with intravenous metoclopramide Open in a separate window Like many other prokinetic drugs, domperidone may show tolerance development on repeated administration, as observed in studies on gastric emptying 23 Nevertheless, domperidone is an important alternative in patients in whom gastroparesis‐related symptoms respond to dopamine antagonists, but metoclopramide has produced unwanted side effects Dec 1, 2018 · Metoclopramide has been suggested as a relatively safe alternative because it has long been considered to have less significant cardiovascular adverse effects We present an older patient who Aug 7, 2018 · Metoclopramide has been suggested as a relatively safe alternative because it has long been considered to have less significant cardiovascular adverse effects We present an older patient who developed severe bradycardia and hypotension shortly after receiving intravenous metoclopramide Is Metoclopramide a safe alternative to domperidone? Is domperidone available in all countries? Apr 27, 2022 · Some common medications used to treat gastroparesis include metoclopramide (Reglan), erythromycin, and domperidone Antiemetics, like promethazine and ondansetron (Zofran), can also be used to help with nausea Other treatments that can help with gastroparesis include some over-the-counter stomach medications and medications that treat pain
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